Patient experiences - UCTC

Patient L., born on 2007, was admitted to the clinic on March 5, 2012 with diagnosis "Smith-Magenis Syndrome".

Neurologist's examination:

The boy has developmental delay since the childhood. Mostly friendly, sometimes aggressive, reacts poorly to the word NO. Does not write or draw. Requests expresses through actions (leads parents to the place of his interest). Neurological status: conscious, smiles to the doctor, makes a peculiar sound (perhaps showing his satisfaction). Follows the instructions, sometimes on the second request. Independently walks around the ward, takes interest in subjects (bed details, lamps). The head is slightly deformed – flat on the back. Eye slots d=s. Pupils d=s. The range of motion of the eyeballs is full. Face asymmetry is not visible. Shows the tip of tongue - the tongue is in midline. Active movements of the limbs in full. No contractures of the joints. No significant changes in muscle tone. Deep reflexes are reduced, Achilles reflexes are not obtained. No pathological foot reflexes.

The patient underwent full 2-days treatment with use of preparation based on stem cells by the method of Prof. Smikodub. Follows the recommendations of post-treatment period. Under regular control of his neurologist and parents.

Letter of mother of Patient L. in six months after the treatment.

"During the first two months after treatment, no improvements were observed (or minimal improvements).
Now almost every day occur some changes in boy's development and behavior, he finds more things interesting, he became more independent, more emotional, he talks a lot in his own language.
Expresses the desire - when he wants something, he takes his mother's hand and with finger points to the thing (e.g., if he wants to walk, he points to shoes, etc.)
Changes in emotions - he expresses disappointment when his mother leaves him in a kindergarten, takes her hand (previously remained indifferent); he expresses more emotions to his parents.
Began to sing - without specific words, but it is clear that he is singing (as sing children, who cannot pronounce the words).
Twice he cried like a normal baby, earlier he only grizzled and mooed.
Started watching cartoons (previously he perceived only music from cartoons) – he can long-term and focused look at the screen, tries to finish the sentence.
Previously he did not come up the steps - now he can go upstairs holding on to the rail (downstairs - fears).
Sleep without waking up the whole night (before got up at 5 am).

When he is not satisfied - continues to beat himself.

From September 2012, the boy is going to a special school (for children from 3 to 19 years) – parents have high hopes for this school.

Would like to know what determines when to take the next course of cell therapy? Can the boy undergo the treatment every six months, if such improvements continue?"

Letter of mother of patient I. 16.04.2012

Good afternoon, Dr. Alexander Smikodub.

I want to share the joyof Ilya’s success, and ask some advice.

Once again, many thanks from me and my husband! We can not express in words our gratitude to you!

After the cell treatment, we noticed an obvious progress. Two weeks after the procedure behavior and emotional condition has improved. It was noticed in kindergarten and by speech pathologist, who has been with him for a year. Then everything has stabilized. But 2 months later, in March, Ilya began to surprise us. He suddenly began to draw and sculpt with play dough, and he always goes everywhere with a pencil or pen. At first pictures were incomprehensible, he sculpted from play dough people and they were beautiful. Then, began to appear meaning and form in his pictures. Our son draws the trains and trolley buses on all the walls in the apartment (we permit). And look how he decorated my phone with play dough (photo attached)! Ilya draws in the books, he adds ears to people, and people to cars. He also has began to write letters. While not all, only A, S, M and O.

Especially noticeable changes in behavior and interests during classes with speech pathologist. Studies easily, assiduously and with interest. Kindergarten teachers praise Ilya. He writes, sculpts and draws a lot. Ilya draws each day more beautiful and more legible. Obvious changes in the fingers and hands have occurred over the last 3-4 weeks!

  He himself says that the picture shows the subway, and there is a girl in it. Ilya draws people in a strange way, he was not taught to draw them right, it is his personal observations.

Fine and gross motor skills, cognitive interest and acumen have improved. He even learned how to play computer games, he is keeping pace with pressing the keys, looking at the screen, not the keyboard. But it is pretty easy to distract from the game and begin to sculpt or paint.

The speech become better, he answers the questions, asks the questions, asks to take him to the waterpark or go to the railway station to see the trains. Far only I understand him, but he is already planning how to spend the weekend!

Constantly mutters, talks. Makes sentences about the pictures. We even ventured to send our son to a normal school. In Russian class with additional hours of individual training after school. His behavior is quite, adequate and social. So far, only his speech lags far behind his peers. Otherwise, on the lessons he will sit still, will not disturb other pupils, some of material will learn and remember. If it will be necessary, we will leave him for 2nd year of education.

We always notice changes in our son’s condition after each course of rehabilitation, but this time, it’s just miracles! I want to ask, when we can or need to undergo a second course of fetal stem cell therapy? We'd like to continue to catch up his peers by seven-league steps.

Once again, thank you so much!

Letter of mother of patient I. 21.04.2013

Good day, Dr. Alexander Smikodub.

So I want to share with you my emotions. I bought colored play dough, and in a 5 minutes, he made a bus fleet. I was just in shock. His fine motor skills, and manifestations of fantasy please me to tears.

Even 3 days ago this could not be done. And the main thing is that everything is understandable - yellow and white buses, at the rear - red lanterns, and black wheels! He invented that himself. In kindergarten, they are taught kids to sculpt apples, carrots, but Ilya already knows how to sculpt buses and people. Not everyone of Ilya peer can sculpt, but with his problems – it is a rarity. And the day before yesterday our speech therapist praised Ilya, he has written letters to teacher’s dictation. She said, "If things go on like now, soon he will write the words".

Thanks again to you and your team for the health care of our son!