In the mid-90s a group of doctors and biologists of Unique Сell Treatment Clinic headed by Professor Alexander Smikodub started the study of the use of stem cells for the treatment of anemia of various kinds. This eventually created the preparations based on stem cells of fetal origin and developed innovative methods of treatment with these preparations. Twenty years of treatment experience confirmed the high efficiency of the therapy of anemia with preparations based on stem cells of fetal origin by Prof. Smikodub.
Anemia is pathological condition characterized by low hemoglobin and / or red blood cells per unit volume of blood. Hemoglobin, of which consist red blood cells or erythrocytes is the main transport protein for the transport of oxygen from the lungs to the body tissues. Therefore, hemoglobin decrease below 110 g / l leads to hypoxia (oxygen deficiency) of all organs. Anemia is the most common hematological disease and nearly always is secondary.
Symptoms of anemia and its clinical signs are non-specific and often patients don’t guess of its presence until they make a routine complete blood count. The main "anemic" manifestations are weakness, fatigue, drowsiness, tinnitus, headaches and dizziness, palpitations, pain in the heart, on examination pale skin and visible mucous membranes, plasticity of face. These symptoms depend on the cause, severity, speed of development and adaptation of the organism.
There are about 400 types of anemia, however, for the convenience of clinical use, there are three main groups:
1) Due to blood loss (posthemorrhagic);
2) Caused by hereditary or acquired disorders of red blood cell production and / or synthesis of hemoglobin;
3) Caused by increased destruction of red blood cells (hemolytic).
More often, there are so-called iron deficiency anemia. Hemoglobin consists of iron and protein, and when the body loses more iron than receives with food, the synthesis of hemoglobin decreases. "Physiological" iron loss can occur for example to women during pregnancy, lactation, menstruation, to children at prematurity, in the period of active growth and puberty, refusal to eat. The most common pathological cause of iron deficiency in the human body is chronic persistent, long-term, though minor bleeding (in diseases of the gastrointestinal tract, uterine, renal, pulmonary, nasal). Iron deficiency anemia occurs to donors who donate blood constantly. Very often, anemic syndrome observes in cancer due to the disease itself or as a complication of radiation and chemotherapy. Certainly the most effective method of treatment of anemia is primarily etiotropic treatment - eliminating of the cause of the disease. However, it is often impossible to eliminate the pathological cause of anemia and in these cases a pathogenic or "replacement" therapy can be used.
The main task of "replacement" treatment is to restore the level of hemoglobin in the shortest time. The simplest and most common method of treatment is a transfusion of blood or blood components.
Fetal stem cells therapy of anemia conducted in the UCTC clinic, is a serious alternative to blood transfusion in this treatment when using of other conventional methods is impossible or does not give the expected efficiency. Fetal stem cells effectively restore hematopoietic system due to their own reproduction and differentiation to various missing blood cells (erythrocytes, platelets and leukocytes). Also, during our therapy due to discharge of biologically active growth factors which are in suspension of fetal stem cells, occurs growth stimulation of own reserves of bone marrow stem cells and recovers production of healthy blood cells. The immune system regenerates, strengthening in general weakened by hypoxia patient’s body and eliminating the autoimmune disease process that has great importance in the development of acquired hemolytic anemias. This treatment provides a fast and stable correction of hematopoiesis that allows to reduce quickly the "oxygen starvation" of internal organs, to improve the quality of life of the patient, to restore the ability to work. In comparison with blood transfusions and other conventional methods of treatment of anemia syndrome, complex therapy using preparations based on fetal stem cells provides the highest quality and long-term clinical effect of the vanishing of anemia or its significant reduction. This is especially true in cases of severe aplastic anemia when there is complete suppression of their own hematopoietic system, and "refresher courses" are the only way to maintain the normal functioning of the human organism.