Cell therapy for the patients with myelodysplasia

When the person has a small amount of platelets, which is abnormal for the condition of a healthy person, he suffers from thrombocytopenia. Thanks to platelets the blood clots in the body therefore patients may have bleeding often. There can be different causes for this condition (myelodysplasia) but the main ones are the following:

• When the level of platelets is not sufficient in the bone marrow
• When the level of breakdown of platelets in the blood is too high
• When the level of platelets breakdown is high in the liver or spleen

In other words, wrong development of blood cells in the marrow bone can bring to myelodysplasia.

Let us regard what causes the condition when the person suffers from insufficient platelets in the bone marrow. Prior to myelodysplasia the patient can have aplastic anemia, leukemia, folate or vitamin B12 deficiency. Sometimes infections in the bone marrow can cause the problem, but such cases are very rare.

The doctor should determine first of all, what exactly caused this condition. In some cases the treatment with definite drugs brings to the situation when there are not enough platelets in the bone marrow. Chemotherapy treatment, for instance, can produce such effect.

When the breakdown of platelets is too high, it can be provoked by swollen spleen (hypersplenism), or when the person has disseminated intravascular coagulation, immune thrombocytopenic purpura and noimmune drug induced thrombocytopenia, thrombotic thrombocytopenic purpura.

Sometimes the person does not have symptoms of myelodysplasia at all or they can involve bruising, bleeding in the gums, mouth and nose and rash.

Medical examination is necessary during which the patient has to answer the questions concerning symptoms. The doctor should study the medical history. The patient passes complete blood count test, PTT and PT blood clotting studies. The doctor also appoints biopsy and a test for platelet-associated antibodies to determine if antibodies are not directed against your platelets.

Much depends upon the diagnosis and the cause of the condition (myelodysplasia). The goal of the doctors is to stop the bleeding and to thwart it. Therefore the transfusion can be appointed.

The condition of the patient is also important as far as the outcome of treatment is concerned.

It must be noted that myelodysplasia is risky and hemorrhage that can complicate the condition of the patient can bring to undesirable consequences. When the patient has bleeding in the brain or it occurs in the gastrointestinal tract then it can bring to lethal outcome. Under the circumstances the right treatment will determine the outcome of the disease.

Cell therapy is one of most highly effective treatment courses when the patient wants to get rid of myelodysplasia and raise his quality of life to a higher level.